Wouter J de Jonge Selected Research

alpha7 Nicotinic Acetylcholine Receptor

5/2010	Selective alpha7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis.
9/2009	Alpha7 cholinergic-agonist prevents systemic inflammation and improves survival during resuscitation.
5/2009	The alpha7 nicotinic acetylcholine receptor on fibroblast-like synoviocytes and in synovial tissue from rheumatoid arthritis patients: a possible role for a key neurotransmitter in synovial inflammation.
10/2007	Activation of the cholinergic anti-inflammatory pathway ameliorates postoperative ileus in mice.

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Wouter J de Jonge Research Topics

Disease

30	Inflammation (Inflammations) 09/2021 - 10/2003
15	Colitis 06/2022 - 01/2004
10	Ileus 06/2021 - 09/2005
7	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 10/2022 - 12/2010
6	Crohn Disease (Crohn's Disease) 10/2022 - 01/2015
6	Hypersensitivity (Allergy) 01/2019 - 01/2013
5	Sepsis (Septicemia) 03/2021 - 10/2003
3	Ulcerative Colitis 03/2022 - 01/2015
3	Anastomotic Leak 12/2018 - 01/2015
2	Wounds and Injuries (Trauma) 09/2022 - 06/2021
2	Neoplasms (Cancer) 04/2021 - 09/2009
2	Weight Loss (Weight Reduction) 04/2021 - 12/2015
2	Pediatric Crohn's disease 01/2021 - 11/2020
2	Dysbiosis 01/2021 - 01/2016
2	Rheumatoid Arthritis 01/2021 - 05/2009
2	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 01/2019 - 05/2015
2	Eosinophilic Esophagitis 09/2015 - 11/2014
1	Gastroschisis 09/2022
1	Short Bowel Syndrome 09/2022
1	Surgical Wound Infection 09/2022
1	Pouchitis 09/2021
1	Critical Illness (Critically Ill) 03/2021
1	Malnutrition (Nutritional Deficiencies) 01/2021
1	Arthralgia (Joint Pain) 01/2021
1	Confusion (Bewilderment) 01/2021
1	Necrotizing Enterocolitis 11/2020
1	Virus Diseases (Viral Diseases) 01/2020
1	Pain (Aches) 01/2019
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2019
1	Atherosclerosis 01/2019
1	Visceral Leishmaniasis (Kala Azar) 01/2019
1	Abdominal Pain (Pain, Abdominal) 01/2019
1	Endotoxemia 01/2019
1	Pneumonia (Pneumonitis) 01/2018

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 12/2021 - 12/2008
6	CytokinesIBA 11/2019 - 05/2010
5	Dextrans (Dextran)FDA Link 05/2022 - 05/2010
5	Pharmaceutical PreparationsIBA 04/2021 - 05/2010
5	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2020 - 05/2009
4	SodiumIBA 05/2022 - 05/2010
4	alpha7 Nicotinic Acetylcholine ReceptorIBA 05/2010 - 10/2007
3	Dextran SulfateIBA 06/2022 - 12/2015
3	Peroxidase (Myeloperoxidase)IBA 09/2005 - 10/2003
2	Amino Acids FDA Link 10/2022 - 11/2020
2	Histone Deacetylase InhibitorsIBA 05/2022 - 01/2019
2	Anti-Bacterial Agents (Antibiotics)IBA 08/2021 - 03/2021
2	AntibodiesIBA 01/2021 - 09/2005
2	Drinking WaterIBA 11/2019 - 05/2010
2	LipidsIBA 01/2019 - 01/2018
2	Syk KinaseIBA 10/2017 - 11/2013
2	GlucansIBA 10/2017 - 12/2015
2	sym-trinitrobenzeneIBA 01/2015 - 05/2010
2	Sulfonic AcidsIBA 01/2015 - 01/2004
2	AcidsIBA 08/2014 - 05/2010
2	doxantrazoleIBA 11/2013 - 08/2004
2	Cholinergic Agents (Cholinergics)IBA 01/2013 - 09/2010
2	A-factor (Streptomyces)IBA 01/2012 - 12/2008
2	Nicotine FDA Link 05/2010 - 10/2007
2	AR-R 17779IBA 05/2010 - 10/2007
2	Peptides (Polypeptides)IBA 01/2010 - 12/2008
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2010 - 12/2008
2	NeuropeptidesIBA 01/2010 - 12/2008
2	Ketotifen (Ketotifene)FDA Link 09/2009 - 08/2004
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2008 - 10/2003
1	KynurenineIBA 10/2022
1	CeramidesIBA 10/2022
1	IntegrinsIBA 09/2021
1	Doxycycline (Periostat)FDA LinkGeneric 08/2021
1	Amoxicillin (Wymox)FDA LinkGeneric 08/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2021
1	Metronidazole (Metric)FDA LinkGeneric 08/2021
1	Vancomycin FDA LinkGeneric 08/2021
1	curdlanIBA 04/2021
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 04/2021
1	16S Ribosomal RNAIBA 03/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 11/2020
1	Angiotensin-Converting Enzyme 2IBA 01/2020
1	Acetylcholine (Acetylcholine Chloride)FDA Link 11/2019
1	Interleukin-10 (Interleukin 10)IBA 01/2019
1	salicylhydroxamic acid (SHAM)IBA 01/2019
1	Capsaicin (Zostrix)FDA Link 01/2019
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2019
1	miltefosine (Impavido)IBA 01/2019
1	LipopolysaccharidesIBA 01/2019
1	Histamine (Histamine Dihydrochloride)FDA Link 01/2019
1	Interleukin-6 (Interleukin 6)IBA 01/2019
1	Nystatin (Mycostatin)FDA LinkGeneric 10/2017
1	C-Type Lectins (C-Type Lectin)IBA 10/2017
1	Fluconazole (Zonal)FDA LinkGeneric 10/2017
1	locked nucleic acidIBA 01/2017

Therapy/Procedure

6	Enteral Nutrition (Feeding, Tube) 10/2022 - 01/2015
5	Therapeutics 08/2021 - 12/2010
3	Vagus Nerve Stimulation 11/2019 - 01/2019
2	Fecal Microbiota Transplantation 03/2022 - 10/2017
2	Sympathectomy (Sympathectomies) 06/2021 - 01/2019
2	Length of Stay 12/2018 - 01/2018
1	Enterostomy 09/2022
1	Restorative Proctocolectomy 09/2021
1	Vagotomy 01/2019